Global differences in the management of ...
Type de document :
Article dans une revue scientifique: Article original
PMID :
URL permanente :
Titre :
Global differences in the management of alcohol-associated hepatitis.
Auteur(s) :
Blaney, H. [Auteur]
Díaz, L. A. [Auteur]
Li, N. [Auteur]
Malhi, G. [Auteur]
Mortuza, R. [Auteur]
Qi, X. [Auteur]
Kulkarni, A. V. [Auteur]
Bataller, R. [Auteur]
Cabezas, J. [Auteur]
Louvet, Alexandre [Auteur]
Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286
Tapper, E. B. [Auteur]
Arab, Juan Pablo [Auteur]
Pontificia Universidad Católica de Chile [UC]
Díaz, L. A. [Auteur]
Li, N. [Auteur]
Malhi, G. [Auteur]
Mortuza, R. [Auteur]
Qi, X. [Auteur]
Kulkarni, A. V. [Auteur]
Bataller, R. [Auteur]
Cabezas, J. [Auteur]
Louvet, Alexandre [Auteur]

Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286
Tapper, E. B. [Auteur]
Arab, Juan Pablo [Auteur]
Pontificia Universidad Católica de Chile [UC]
Titre de la revue :
The Lancet Gastroenterology & Hepatology
Nom court de la revue :
Lancet Gastroenterol Hepatol
Numéro :
9
Pagination :
972-974
Éditeur :
Elsevier
Date de publication :
2024-10-14
ISSN :
2468-1253
Discipline(s) HAL :
Sciences du Vivant [q-bio]
Résumé en anglais : [en]
Alcohol-associated hepatitis is characterised by jaundice and malaise in individuals with excessive and chronic alcohol intake, and is associated with high short-term mortality.1 Specific treatments for alcohol-associated ...
Lire la suite >Alcohol-associated hepatitis is characterised by jaundice and malaise in individuals with excessive and chronic alcohol intake, and is associated with high short-term mortality.1 Specific treatments for alcohol-associated hepatitis are scarce, and treatment for the underlying alcohol use disorder (AUD) is often neglected in clinical practice.2 Management of severe alcohol-associated hepatitis is mainly based on supportive therapy, including nutrition and treating infections as they arise. Corticosteroids have been used to treat alcohol-associated hepatitis since the 1970s and remain the only effective treatment, although multiple studies show inadequate efficacy.1 Early liver transplantation has emerged as a novel strategy to improve survival in severe alcohol-associated hepatitis,3 yet access is not universally available.4 Little is known about international practice variations in managing alcohol-associated hepatitis. We aimed to examine practice patterns regarding the treatment of alcohol-associated hepatitis and adherence to current clinical guidelines and evidence.Lire moins >
Lire la suite >Alcohol-associated hepatitis is characterised by jaundice and malaise in individuals with excessive and chronic alcohol intake, and is associated with high short-term mortality.1 Specific treatments for alcohol-associated hepatitis are scarce, and treatment for the underlying alcohol use disorder (AUD) is often neglected in clinical practice.2 Management of severe alcohol-associated hepatitis is mainly based on supportive therapy, including nutrition and treating infections as they arise. Corticosteroids have been used to treat alcohol-associated hepatitis since the 1970s and remain the only effective treatment, although multiple studies show inadequate efficacy.1 Early liver transplantation has emerged as a novel strategy to improve survival in severe alcohol-associated hepatitis,3 yet access is not universally available.4 Little is known about international practice variations in managing alcohol-associated hepatitis. We aimed to examine practice patterns regarding the treatment of alcohol-associated hepatitis and adherence to current clinical guidelines and evidence.Lire moins >
Langue :
Anglais
Audience :
Internationale
Vulgarisation :
Non
Établissement(s) :
Université de Lille
Inserm
CHU Lille
Inserm
CHU Lille
Date de dépôt :
2025-01-01T22:04:42Z
2025-01-15T09:00:28Z
2025-01-15T09:00:28Z