Titre :

Monitoring of inflammatory bowel disease in 2019: a french consensus for clinical practice

Auteur(s) :

Bonnaud, Guillaume [Auteur]
Bouhnik, Yoram [Auteur]
Hagege, Herve [Auteur]
Hebuterne, Xavier [Auteur]
Pariente, Benjamin [Auteur]
Roblin, Xavier [Auteur]
Peyrin-Biroulet, Laurent [Auteur]

Titre de la revue :

Digestive and liver disease . official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

Nom court de la revue :

Dig Liver Dis

Date de publication :

2020-05-05

ISSN :

1878-3562

Discipline(s) HAL :

Sciences du Vivant [q-bio]

Résumé en anglais : [en]

For inflammatory bowel disease, traditional dose escalation approaches that are based on clinical symptoms are being replaced by more aggressive treat-to-target approaches, in which treatment is adjusted promptly when ...
Lire la suite >For inflammatory bowel disease, traditional dose escalation approaches that are based on clinical symptoms are being replaced by more aggressive treat-to-target approaches, in which treatment is adjusted promptly when predefined clinical and mucosal targets are not met. There is, however, an ongoing need to combine up-to-date treat-to-target strategies with easy-to-implement recommendations. Herein, we present consensus-recommendations for treatment targets that reflect current best practices in France. Methods Thirty-four gastroenterologists practicing in France participated in a meeting during which consensus statements about treat-to-target strategies for following patients with Crohn's disease (CD) and ulcerative colitis were developed. Targets, their definitions, and the timeframes for reaching them were defined. Consensus was defined as ≥66% of experts agreeing with a statement. Results For both diseases, the agreed targets were: patient related outcomes on disease (PRO-1), patient related outcomes on gastrointestinal symptoms (PRO-2), endoscopic healing and biomarkers of inflammation. Nutritional status has been defined as a target for CD only. Histological healing and transmural healing were not defined as targets. Deadlines to achieve targets and monitoring frequency have been agreed as well. Conclusions These consensus statements provide simple, easy-to-follow guidelines that should help gastroenterologists in France implement treat-to-target approaches, optimize treatments, and thus, reduce the burden of disease.Lire moins >

Langue :

Anglais

Audience :

Internationale

Vulgarisation :

Non

Établissement(s) :

CHU Lille
Inserm
Université de Lille

Collections :

• Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286

Date de dépôt :

2021-07-06T12:45:08Z