Combined alcoholic and non-alcoholic ...
Document type :
Article dans une revue scientifique: Article de synthèse/Review paper
PMID :
Permalink :
Title :
Combined alcoholic and non-alcoholic steatohepatitis
Author(s) :
Ntandja Wandji, Line [Auteur]
Institute for Translational Research in Inflammation - U 1286 [INFINITE]
Gnemmi, Viviane [Auteur]
Cancer Heterogeneity, Plasticity and Resistance to Therapies (CANTHER) - UMR 9020 - UMR 1277
Miniaturisation pour la Synthèse, l'Analyse et la Protéomique (MSAP) - USR 3290
Mathurin, Philippe [Auteur]
Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286
Louvet, Alexandre [Auteur]
Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286
Institute for Translational Research in Inflammation - U 1286 [INFINITE]
Gnemmi, Viviane [Auteur]

Cancer Heterogeneity, Plasticity and Resistance to Therapies (CANTHER) - UMR 9020 - UMR 1277
Miniaturisation pour la Synthèse, l'Analyse et la Protéomique (MSAP) - USR 3290
Mathurin, Philippe [Auteur]

Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286
Louvet, Alexandre [Auteur]

Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286
Journal title :
JHEP Reports Innovation in Hepatology
Abbreviated title :
JHEP Rep
Volume number :
2
Pages :
100101
Publication date :
2020-06-01
ISSN :
2589-5559
Keyword(s) :
diabetes
obesity
metabolic syndrome
NAFLD
NASH
ASH
Alcohol
ALD
obesity
metabolic syndrome
NAFLD
NASH
ASH
Alcohol
ALD
English keyword(s) :
Alcohol
ALD
ASH
NASH
NAFLD
metabolic syndrome
obesity
diabetes
ALD
ASH
NASH
NAFLD
metabolic syndrome
obesity
diabetes
HAL domain(s) :
Sciences du Vivant [q-bio]
English abstract : [en]
While metabolic syndrome and alcohol consumption are the two main causes of chronic liver disease, one of the two conditions is often predominant, with the other acting as a cofactor of morbimortality. It has been shown ...
Show more >While metabolic syndrome and alcohol consumption are the two main causes of chronic liver disease, one of the two conditions is often predominant, with the other acting as a cofactor of morbimortality. It has been shown that obesity and alcohol act synergistically to increase the risk of fibrosis progression, hepatic carcinogenesis and mortality, while genetic polymorphisms can strongly influence disease progression. Based on common pathogenic pathways, there are several potential targets that could be used to treat both diseases; based on the prevalence and incidence of these diseases, new therapies and clinical trials are needed urgently.Show less >
Show more >While metabolic syndrome and alcohol consumption are the two main causes of chronic liver disease, one of the two conditions is often predominant, with the other acting as a cofactor of morbimortality. It has been shown that obesity and alcohol act synergistically to increase the risk of fibrosis progression, hepatic carcinogenesis and mortality, while genetic polymorphisms can strongly influence disease progression. Based on common pathogenic pathways, there are several potential targets that could be used to treat both diseases; based on the prevalence and incidence of these diseases, new therapies and clinical trials are needed urgently.Show less >
Language :
Anglais
Audience :
Internationale
Popular science :
Non
Administrative institution(s) :
CHU Lille
CNRS
Inserm
Université de Lille
CNRS
Inserm
Université de Lille
Collections :
Submission date :
2021-07-06T12:50:50Z
2024-01-22T14:37:45Z
2024-01-22T14:37:45Z
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