Does exposure to inflammatory particles modify the pattern of anion in exhaled breath condensate?

Type de document :

Article dans une revue scientifique: Article original

DOI :

10.1088/1752-7163/ab5d88

PMID :

URL permanente :

http://hdl.handle.net/20.500.12210/59741

Titre :

Does exposure to inflammatory particles modify the pattern of anion in exhaled breath condensate?

Auteur(s) :

Sauvain, Jean-Jacques [Auteur]
Edme, Jean-Louis [Auteur]

Wild, Pascal [Auteur]
Suarez, Guillaume [Auteur]
De Paula Alvez Bezerra, Olivia Maria [Auteur]
Talvani, Andre [Auteur]
Algranti, Eduardo [Auteur]
Carneiro, Ana Paula Scalio [Auteur]
Chérot-Kornobis, Nathalie [Auteur]

Sobaszek, Annie [Auteur]

IMPact de l'Environnement Chimique sur la Santé humaine (IMPECS) - ULR 4483
Hulo, Sebastien [Auteur]

Titre de la revue :

Journal of breath research

Nom court de la revue :

J Breath Res

Date de publication :

2019-11-29

ISSN :

1752-7163

Mot(s)-clé(s) :

quartz
small chain fatty acids
exhaled breath condensate
ion chromatography
metabolism
soapstone

Discipline(s) HAL :

Sciences du Vivant [q-bio]

Résumé en anglais : [en]

Exposure to environmental and occupational particulate matter (PM) induces health effects on the cardio-pulmonary system. In addition, associations between exposure to PM and metabolic syndromes like diabetes mellitus or ...
Lire la suite >Exposure to environmental and occupational particulate matter (PM) induces health effects on the cardio-pulmonary system. In addition, associations between exposure to PM and metabolic syndromes like diabetes mellitus or obesity are now emerging in the literature. Collection of exhaled breath condensate (EBC) is an appealing non-invasive technique to sample pulmonary fluids. This hypothesis-generating study aims to (1) validate an ion chromatography method allowing the robust determination of different metabolism-related molecules (lactate, formate, acetate, propionate, butyrate, pyruvate, nitrite, nitrate) in EBC; (2) apply this method to EBC samples collected from workers exposed to quartz (a known inflammatory particle), to soapstone (a less inflammatory particle than quartz), as well as to controls. A multi-compound standard solution was used to determine the linearity range, detection limit, repeatability and bias from spiked EBC. The biological samples were injected without further treatment into an ion chromatograph with a conductivity detector. RTube®Lire moins >

Langue :

Anglais

Audience :

Internationale

Vulgarisation :

Non

Établissement(s) :

CHU Lille
Institut Pasteur de Lille
Université de Lille

Collections :

IMPact de l'Environnement Chimique sur la Santé humaine (IMPECS) - ULR 4483

Date de dépôt :

2022-02-02T10:24:25Z

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Sauvain et al.pdf
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